Eduardo Aluicio‐Sarduy

Bispecific GD2xB7-H3 Antibody Improves Tumor Targeting and Reduces Toxicity while Maintaining Efficacy for Neuroblastoma

This paper describes a bispecific antibody that targets GD2 and B7-H3 to improve tumor targeting and reduce toxicity in neuroblastoma treatment.

Characterization and Calibration of the iQID Digital Autoradiography System for Direct Quantitative Imaging of Beta-Emitters in Tissue Samples

This paper characterizes and calibrates the iQID digital autoradiography system for quantitative imaging of 177Lu beta-emitters, showing high accuracy and resolution for small-scale features.

Tuning the Structural Properties of a Single-Domain Antibody Scaffold for Improved Fibroblast Activation Protein Targeting

This study engineers single-domain antibodies to improve targeting of FAP, showing that valency and molecular weight affect tumor uptake and biodistribution.

A MET-Targeted Variable New Antigen Receptor Theranostic for Non-Small Cell Lung Cancer

This paper develops a shark-derived VNAR-based theranostic agent for MET-altered NSCLC, showing imaging and therapeutic efficacy in preclinical models.

Effects of clinically relevant radionuclides on the activation of a type I interferon response by radiopharmaceuticals in syngeneic murine tumor models

This study examines how different radionuclides affect the type I interferon response in tumor models and shows that 225Ac enhances immunotherapy response via STING-dependent mechanisms.

Development of FAP-targeted theranostics discovered by next-generation sequencing-augmented mining of a novel immunized VNAR library

The paper develops FAP-targeted theranostics using VNARs from a shark antibody library, showing high affinity and efficacy in vitro and in vivo.

Bispecific GD2 x B7-H3 Antibody Improves Tumor Targeting and Reduces Toxicity while Maintaining Efficacy for Neuroblastoma