High-throughput screening in hiPSC-cardiac models reveals cardiomyocyte-specific cell cycle regulatory mechanisms
Francesca Butera, Bryce Hassett, Rachel Morris, Jerico Revote, Hannah Huckstep, Lina H.H. Le, Jack Leerson, Thomas Martinez, Stephanie R. Hyslop, Sebastian Bass-Stringer, Antonia T.L. Zech, Tabitha Cree, Rebecca J. Sutton, Ivy Kim Chiang, Eddy Kizana, , Enzo R. Porrello
The paper identifies a compound that selectively promotes cardiomyocyte proliferation through specific cell cycle mechanisms without affecting other cell types.
bioRxiv · Aug 17, 2026 · PreprintCell Biology