Jerico Revote

High-throughput screening in hiPSC-cardiac models reveals cardiomyocyte-specific cell cycle regulatory mechanisms

The paper identifies a compound that selectively promotes cardiomyocyte proliferation through specific cell cycle mechanisms without affecting other cell types.

TCR_Explore: a novel webtool for T cell receptor repertoire analysis

TCR_Explore is a webtool for TCR repertoire analysis that automates quality control and analysis, enabling non-expert users to generate publication-ready figures.

MonaGO: a novel Gene Ontology enrichment analysis visualisation system

MonaGO provides an interactive web-based visualization system for gene ontology enrichment analysis, offering dynamic clustering and customizable outputs to improve interpretation of results.

Predicting and validating protein degradation in proteomes using deep learning

The paper develops a deep learning model to predict protein degradation by proteases and UVR/ROS in human skin, validated against experimental data and integrated into a web tool for proteome susceptibility analysis.

Resilience to dominant genetic disease in the healthy elderly

The paper screens healthy elderly individuals to identify those resilient to genetic diseases despite high genetic risk, finding 141 individuals without associated disease despite pathogenic variants.

PRISMOID: a comprehensive 3D structure database for post-translational modifications and mutations with functional impact

PRISMOID is a 3D structure database for post-translational modifications and mutations, providing structural and functional insights into PTM sites and their interactions.