Author

Ellen B. Keen

Murdoch Children's Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1

Frequent Co-Authors

David A. ElliottiD· 2 shared Enzo R. PorrelloiD· 2 shared Hannah HuckstepiD· 2 shared James W. McNamaraiD· 2 shared Lina H.H. LeiD· 2 shared Richard J. MillsiD· 2 shared Sean J. HumphreyiD· 2 shared Alejandro HidalgoiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersPhysiology

David A. ElliottORCID

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Author profile →

2 papers

Recent·Most cited

Alpha Protein Kinase 3 Gene Therapy Restores Heart Function in Mouse and Human Models of Cardiomyopathy

James W. McNamara, Ellen B. Keen, Rebecca Sutton, Yinghan She, Hannah Huckstep, Lina H.H. Le, Neda R. Mehdiabadi, Madhavan S. Venkatesh, Brendan Griffen, Richard J. Mills, Christina V. Theodoris, James E. Hudson, Drew M. Titmarsh, Sean J. Humphrey, Enzo R. Porrello, David A. Elliott

This study shows that gene therapy with AAV-ALPK3 improves heart function in mouse and human models of cardiomyopathy caused by ALPK3 variants.

Nature Cardiovascular Research · Aug 19, 2026Peer-reviewedPhysiology

High-throughput screening in hiPSC-cardiac models reveals cardiomyocyte-specific cell cycle regulatory mechanisms

Francesca Butera, Bryce Hassett, Rachel Morris, Jerico Revote, Hannah Huckstep, Lina H.H. Le, Jack Leerson, Thomas Martinez, Stephanie R. Hyslop, Sebastian Bass-Stringer, Antonia T.L. Zech, Tabitha Cree, Rebecca J. Sutton, Ivy Kim Chiang, Eddy Kizana, , Enzo R. Porrello

The paper identifies a compound that selectively promotes cardiomyocyte proliferation through specific cell cycle mechanisms without affecting other cell types.

bioRxiv · Aug 17, 2026 · PreprintCell Biology