Physiological analysis of the mechanism of Ci transcription factor activation through multiple Fused phosphorylation sites in Hedgehog signal transduction
H.-Y. Kim, Jamie C Little, Jason Li, Bryna Patel, Daniel Kalderon
The paper investigates how phosphorylation sites on Ci regulate its activation in Drosophila through interactions with Fu kinase and Su(fu), revealing new insights into Ci conformation and activation mechanisms.
bioRxiv · Jan 24, 2025 · PreprintDevelopmental Biology