Author

C. A. C. Peretz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

C. C. Smith· 3 shared C. L. Delley· 2 shared A. Abate· 1 shared A. C. Logan· 1 shared A. E. Perl· 1 shared A. Koh· 1 shared A. Olshen· 1 shared A. R. Abate· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

C. C. Smith

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 15, 2023

Multiomic Single Cell Sequencing Identifies Stemlike Nature of Mixed Phenotype Acute Leukemia and Provides Novel Risk Stratification

C. A. C. Peretz, V. E. Kennedy, A. Walia…·C. C. Smith

The paper uses multiomic single-cell profiling to show MPAL blasts have a stem-like transcriptional profile linked to poor prognosis and develops a gene score for clinical risk stratification.

DOI 10.1101/2023.05.15.540305

humanscRNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintDec 1, 2022

Allosteric SHP2 Inhibition Increases Apoptotic Dependency on BCL2 and Synergizes with Venetoclax in FLT3- and KIT- Mutant AML

B. Popescu, C. Stahlhut, T. C. Tarver…·C. C. Smith

This study shows that combining SHP2 and BCL2 inhibition synergistically kills FLT3- and KIT-mutant AML cells and xenografts.

DOI 10.1101/2022.12.01.518665

humanproteomics

𝕏 PostBluesky

Cancer BiologybioRxivFeb 26, 2020

Joint profiling of DNA and proteins in single cells to dissect genotype-phenotype associations in leukemia

B. Demaree, C. L. Delley, H. N. Vasudevan…·A. R. Abate

This study introduces DAb-seq, a method to simultaneously profile DNA and protein in single cells, and applies it to analyze leukemia patient data to reveal genotype-phenotype dynamics.

DOI 10.1038/s41467-021-21810-3

humanscRNA-seq

𝕏 PostBluesky