Ectopic expression of pericentric HSATII RNA results in nuclear RNA accumulation, MeCP2 recruitment, and cell division defects
C. C. Landers, C. A. Rabeler, E. K. Ferrari, L. R. D'Alessandro, D. D. Kang, J. Malisa, S. M. Bashir, D. M. Carone
This study shows that ectopic HSATII RNA expression in normal cells causes nuclear RNA accumulation, MeCP2 recruitment, and cell division defects similar to those in cancer cells.
bioRxiv · Apr 30, 2020Cell Biology