Silencing cryptic specialized metabolism in Streptomyces by the nucleoid-associated protein Lsr2
E. J. Gehrke, X. Zhang, S. M. Pimentel-Elardo, A. R. Johnson, C. A. Rees, S. E. Jones, Hindra, S. S. Gehrke, S. Turvey, S. Boursalie, J. E. Hill, E. E. Carlson, J. R. Nodwell, M. A. Elliot
This study shows that Lsr2 represses specialized metabolic gene clusters in Streptomyces, revealing its role in silencing cryptic metabolism and controlling the production of secondary metabolites.
bioRxiv · Apr 22, 2019Microbiology