C. Aime

Hotwiring integrin endocytosis acutely modulates cell interactions

This study uses hot-wired endocytosis to acutely downregulate 5{beta}1 integrins, showing reduced cell area, fibronectin uptake, and slower tumor spheroid compaction.

Phylogenomics, biogeography, and trait evolution of the Boletaceae (Boletales, Agaricomycetes, Basidiomycota)

This study presents a genome-wide phylogenetic analysis of Boletaceae fungi, revealing their evolutionary history, biogeography, and trait evolution.

The balance between shear flow and extracellular matrix in ovarian cancer-on-chip

This study uses an ovarian tumor-on-chip to investigate how extracellular matrix and shear stress influence tumor cell migration and phenotype, showing ECM's dominant role in migration modes and EMT transition.

Topology of connective tissues: a key parameter in cellular heterogeneity, beyond composition and stiffness

This study creates ECM models with varied topology, composition, and stiffness to study their impact on cellular phenotypes, showing EMT shifts are multidimensional and not solely dependent on single ECM features.

High-throughput tuning of ovarian cancer spheroids for on-chip invasion assays

This paper develops a microfabricated invasion assay for ovarian cancer spheroids to study tumor invasion and drug response.

Multivalent Clustering of Adhesion Ligands in Nanofiber-Nanoparticle Composites

This study demonstrates that clustering bioactive signals on silica nanoparticles enhances fibroblast adhesion on composite hydrogels compared to peptide amphiphile-only matrices.

Electrospinning of pure, native, cross-linker free self-supported collagen membrane

This study reports the electrospinning of pure, native collagen into a self-supported membrane without cross-linkers or polymer support, showing good integrity and cell adhesion properties.