Selective Elimination of Osteosarcoma Cell Lines with Short Telomeres by ATR Inhibitors
T. Goncalves, G. Zoumpoulidou, C. Alvarez-Mendoza, L. C. Collopy, S. J. Strauss, S. Mittnacht, K. Tomita
This study identifies that osteosarcoma cell lines with short telomeres are selectively sensitive to ATR inhibitors, suggesting telomere length as a predictor of drug response.
bioRxiv · Aug 18, 2020Cancer Biology