Author

T. Goncalves

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Sambangi· 1 shared C. Alvarez-Mendoza· 1 shared C. M. Green· 1 shared D. Clynes· 1 shared D. Geschwind· 1 shared D. M. O'Rourke· 1 shared D. Moralli· 1 shared D. Y. Zhang· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCancer Biology

A. Sambangi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Brain-wide neuronal circuit connectome of human glioblastoma

Y. Sun, X. Wang, D. Y. Zhang, Z. Zhang, J. P. Bhattarai, Y. Wang, W. Dong, F. Zhang, K. H. Park, J. Galanaugh, A. Sambangi, Q. Yang, S. H. Kim, G. Wheeler, T. Goncalves, , H. Song

This study shows human glioblastoma cells integrate into brain-wide neuronal circuits, exhibit diverse connectivity, and respond to neuromodulatory inputs like acetylcholine, which promotes invasion and survival.

bioRxiv · Mar 1, 2024Cancer Biology

Loss of FAM111B protease mutated in hereditary fibrosing poikiloderma syndrome negatively regulates telomere length

M. Kliszczak, D. Moralli, J. Jankowska, P. Bryjka, L. Subha, T. Goncalves, S. Hester, R. Fischer, D. Clynes, C. M. Green

This study identifies FAM111B as a regulator of telomere length through interactions with the nuclear pore complex, independent of telomerase, and links its dysfunction to genomic instability in HFP patients.

bioRxiv · Jan 22, 2023 · PreprintCell Biology

Selective Elimination of Osteosarcoma Cell Lines with Short Telomeres by ATR Inhibitors

T. Goncalves, G. Zoumpoulidou, C. Alvarez-Mendoza, L. C. Collopy, S. J. Strauss, S. Mittnacht, K. Tomita

This study identifies that osteosarcoma cell lines with short telomeres are selectively sensitive to ATR inhibitors, suggesting telomere length as a predictor of drug response.

bioRxiv · Aug 18, 2020Cancer Biology