Extracellular vesicle-based vaccine platform displaying native viral envelope proteins elicits a robust anti-SARS-CoV-2 response in mice.
K. Polak, N. Greze, M. Lachat, D. Merle, S. Chiumento, C. Bertrand-Gaday, B. Trentin, R. Z. Mamoun
This study develops an EV-based vaccine platform that displays native SARS-CoV-2 Spike proteins, inducing strong anti-viral responses in mice without adjuvants.
bioRxiv · Oct 28, 2020 · PreprintImmunology