Chemotherapy-induced intestinal injury promotes Galectin-9-driven modulation of T cell function
P. J. Coffer, C. A. Lindemans, A. Cutilli, S. A. Jansen, C. C. de Koning, M. van Hoesel, S. Nierkens, M. Mokry, E. E. Nieuwenhuis, E. Mocholi, A. Hanash
This study shows chemotherapy-induced intestinal damage promotes T cell activation and trafficking via galectin-9, linking epithelial injury to GVHD pathogenesis.
bioRxiv · Apr 30, 2023 · PreprintImmunology