Author

C. C. Faria

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C. Custodia· 2 shared E. Paisana· 2 shared J. Miguens· 2 shared J. Pimentel· 2 shared J. T. Barata· 2 shared R. Cascao· 2 shared R. Roque· 2 shared T. Carvalho· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

C. Custodia

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

UBE2C promotes leptomeningeal dissemination and is a therapeutic target in brain metastatic disease

E. Paisana, R. Cascao, C. Custodia, N. Qin, D. Picard, D. Pauck, T. Carvalho, P. Ruivo, C. Barreto, D. Doutel, J. Cabecadas, R. Roque, J. Pimentel, J. Miguens, J. T. Barata, C. C. Faria

This study identifies UBE2C as a driver of leptomeningeal dissemination in brain metastases and shows that PI3K/mTOR inhibition can prevent its metastatic effects.

bioRxiv · Oct 4, 2022 · PreprintCancer Biology

Patient-derived models of brain metastases recapitulate the histopathology and biology of human metastatic cancers

C. C. Faria, C. Custodia, R. Cascao, E. Paisana, T. Carvalho, P. Pereira, R. Roque, J. Pimentel, J. Miguens, J. T. Barata

This study develops patient-derived xenograft models of brain metastases that replicate human cancer biology and respond to targeted therapies.

bioRxiv · Nov 26, 2020 · PreprintCancer Biology