Harnessing homeostatically active RhoC at cell junctions preserves human endothelial barrier function during inflammation
N. Colas-Algora, P. Munoz-Pinillos, S. Barroso, C. Cacho-Navas, A. Caballero, G. Cerro-Tello, G. de Rivas, M. Gonzalez-Fernandez, I. Jimenez-Alfaro, M. Fresno, C. Ribas, A. Paradela, E. Lopez-Collazo, J.-J. Fernandez, J. Millan
The paper shows that activating RhoC at cell junctions preserves endothelial barrier function during inflammation by enhancing adherens junctions and stabilizing actomyosin.
bioRxiv · May 17, 2024 · PreprintCell Biology