J. Millan

Hippocampal ERK2 dimerization is critical for memory reconsolidation and synaptic plasticity

This study shows that ERK2 dimerization is crucial for memory reconsolidation and synaptic plasticity, with DEL inhibiting dimerization and affecting memory retention differently based on memory strength.

Harnessing homeostatically active RhoC at cell junctions preserves human endothelial barrier function during inflammation

The paper shows that activating RhoC at cell junctions preserves endothelial barrier function during inflammation by enhancing adherens junctions and stabilizing actomyosin.

ICAM-1 nanoclusters regulate hepatic epithelial cell polarity by leukocyte adhesion-independent control of apical actomyosin

This study shows ICAM-1 nanoclusters control hepatic epithelial cell polarity through actomyosin regulation, independent of leukocyte adhesion.

p73 is required for vessel integrity controlling endothelial junctional dynamics through Angiomotin

This study identifies p73 as a regulator of endothelial junction dynamics through Angiomotin, showing its role in maintaining vessel integrity and preventing hyperpermeability.