Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies
C. Caillat, D. Guilligay, J. Torralba, N. Friedrich, J. L. Nieva, A. Trkola, C. Chipot, F. Dehez, W. Weissenhorn
This paper presents the crystal structure of HIV-1 gp41 in a fusion intermediate state, revealing conformational plasticity and how antibodies block membrane fusion.
bioRxiv · Nov 12, 2020Microbiology