Transcriptomically-guided mesendoderm induction of human pluripotent stem cells using a systematically defined culture scheme
R. L. Carpenedo, S. Y. Kwon, R. M. Tanner, J. Yockell-Lelievre, C. Choey, C. Dore, M. Ho, D. J. Stewart, T. J. Perkins, W. L. Stanford
This study introduces a method using single-cell seeding and BMP4/Activin A treatment to induce mesendoderm from hPSCs, showing increased mesoderm and endoderm formation.
bioRxiv · Feb 26, 2019Bioengineering