Author

D. J. Stewart

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Cell Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Research Focus:development & morphogenesis· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Organism:rat· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Y. Deng· 4 shared K. Rowe· 3 shared N. D. Cober· 3 shared D. W. Courtman· 2 shared K. R. Chaudhary· 2 shared L. Wang· 2 shared A. Benavente-Babace· 1 shared A. Yang· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersBioengineering

Y. Deng

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Vicious cycle of hemodynamic perturbation and endothelial injury in development and progression of pulmonary arterial hypertension

Y. Deng, K. R. Chaudhary, A. Yang, K. Kesavan, L. Wang, K. Chathely, D. J. Stewart

This study shows that hemodynamic perturbations and endothelial injury form a cycle driving pulmonary arterial hypertension, which can be reversed by unilateral lung banding.

bioRxiv · Oct 16, 2023 · PreprintPhysiology

Single-cell microencapsulation improves lung retention of endothelial colony forming cells after intravascular delivery and unmasks therapeutic benefit in severe pulmonary arterial hypertension

N. D. Cober, K. R. Chaudhary, Y. Deng, C.-J. Lee, K. Rowe, D. W. Courtman, D. J. Stewart

This study shows that microencapsulation of endothelial colony forming cells (ECFCs) improves their lung retention and therapeutic efficacy in a rat model of pulmonary arterial hypertension.

bioRxiv · Nov 5, 2022Bioengineering

Targeting extracellular vesicle delivery to the lungs by microgel encapsulation

N. D. Cober, K. Rowe, Y. Deng, A. Benavente-Babace, D. W. Courtman, M. Godin, D. J. Stewart

This study encapsulates extracellular vesicles in microgels to enhance their targeted delivery to the lungs, showing prolonged retention and increased uptake by lung cells.

bioRxiv · Sep 9, 2022Bioengineering

Novel Apelin-expressing gCap Endothelial Stem-like Cells Orchestrate Lung Microvascular Repair

R. S. Godoy, D. P. Cook, N. D. Cober, E. McCourt, Y. Deng, L. Wang, K. Schlosser, K. Rowe, D. J. Stewart

This study identifies novel apelin-expressing gCap endothelial stem-like cells that drive lung microvascular repair after endothelial cell ablation by apelin signaling.

bioRxiv · Jul 12, 2021Cell Biology

COMMD1 and PtdIns(4,5)P2 interaction maintain ATP7B copper transporter trafficking fidelity in HepG2 cells

D. J. Stewart, K. K. Short, B. N. Maniaci, J. L. Burkhead

This study shows COMMD1 maintains ATP7B copper transporter trafficking by interacting with PtdIns(4,5)P2, preventing copper accumulation in HepG2 cells.

bioRxiv · Mar 8, 2019Cell Biology

Transcriptomically-guided mesendoderm induction of human pluripotent stem cells using a systematically defined culture scheme

R. L. Carpenedo, S. Y. Kwon, R. M. Tanner, J. Yockell-Lelievre, C. Choey, C. Dore, M. Ho, D. J. Stewart, T. J. Perkins, W. L. Stanford

This study introduces a method using single-cell seeding and BMP4/Activin A treatment to induce mesendoderm from hPSCs, showing increased mesoderm and endoderm formation.

bioRxiv · Feb 26, 2019Bioengineering