Ipl1-controlled attachment maturation regulates Mps1 association with its kinetochore receptor
R. Pleuger, C. Cozma, S. Hohoff, C. Denkhaus, A. Dudziak, F. Kaschani, A. Musacchio, I. R. Vetter, S. Westermann
The paper shows that Ipl1/Aurora B kinase regulates Mps1's release from kinetochores by competing with Dam1 for binding to Ndc80:Nuf2, enabling proper chromosome segregation.
bioRxiv · Oct 30, 2023Cell Biology