Defective pgsA contributes to increased membrane fluidity and cell wall thickening in S. aureus with high-level daptomycin resistance
C. D. Freeman, T. Hansen, R. J. B. Urbauer, B. J. Wilkinson, V. K. Singh, K. M. Hines
This study shows that mutations in pgsA increase membrane fluidity and cell wall thickness in daptomycin-resistant S. aureus, contributing to resistance.
bioRxiv · Apr 11, 2023 · PreprintMicrobiology