K. M. Hines

Lipidomics of homeoviscous adaptation to low temperatures in Staphylococcus aureus utilizing exogenous straight-chain unsaturated fatty acids over biosynthesized endogenous branched-chain fatty acids

This paper shows that Staphylococcus aureus uses exogenous unsaturated fatty acids to enhance growth at low temperatures through lipid remodeling and carotenoid production.

High throughput screening of mesenchymal stromal cell morphological response to inflammatory signals for bioreactor-based manufacturing of extracellular vesicles that modulate microglia

The paper screens MSC morphology in response to inflammatory priming to identify optimal conditions for EV production and microglia modulation in bioreactors.

Defective pgsA contributes to increased membrane fluidity and cell wall thickening in S. aureus with high-level daptomycin resistance

This study shows that mutations in pgsA increase membrane fluidity and cell wall thickness in daptomycin-resistant S. aureus, contributing to resistance.

Endocytosis in Trypanosoma cruzi Depends on Proper Recruitment and Regulation of Functionally Redundant Myosin Motors

This study identifies MyoF and MyoC as functionally redundant myosin motors essential for endocytosis in T. cruzi, with MyAP playing dual roles in myosin targeting and regulation.

Lipidomic and Ultrastructural Characterization of Cell Envelope of Staphylococcus aureus Grown in the Presence of Human Serum

This study characterizes how human serum affects the lipid composition and cell envelope structure of Staphylococcus aureus, showing serum lipids associate with the cell surface but are not fully integrated into the membrane.

Occurrence of cross-resistance and beta-lactam seesaw effect in glycopeptide, lipopeptide, and lipoglycopeptide-resistant MRSA correlates with membrane phosphatidylglycerol levels

The paper investigates the relationship between membrane phosphatidylglycerol levels and cross-resistance, as well as the beta-lactam seesaw effect, in MRSA strains resistant to glycopeptides, lipopeptides, and lipoglycopeptides.

A Vibrio cholerae BolA-like protein is required for proper cell shape and cell envelope integrity

This study identifies IbaG, a BolA-like protein in V. cholerae, as critical for cell shape and envelope integrity through its role in iron-sulfur cluster protein biogenesis.