Phenol Sensing in Nature Modulated via a Conformational Switch Governed by Dynamic Allostery
J. Singh, M. Sahil, S. Ray, C. Dcosta, S. Panjikar, G. Krishnamoorthy, J. Mondal, R. Anand
The paper shows that MopR, an NtrC protein, uses dynamic allostery to sense phenol, altering its conformation and ATPase activity, with implications for evolutionary conservation.
bioRxiv · May 18, 2022Biochemistry