ImmunologybioRxiv
The inflammatory and tumor suppressor SAMD9L acts through a Schlafen-like box to restrict HIV and inhibit cell translation in SAAD/ATXPC
A. Legrand, C. Dahoui, C. De La Myre Mory…·L. Etienne
This paper identifies SAMD9L as an HIV-1 restriction factor that inhibits viral and cellular translation through a Schlafen-like box, with implications for HIV/AIDS and genetic diseases.
DOI 10.1371/journal.pbio.3002696