C. Dunlop

Emergence of active contractile patterns alters monolayer force generation and transmission in response to focal adhesion distribution

This study shows that focal adhesion distribution affects force balance in epithelial monolayers, revealing non-uniform contractile patterns that alter force transmission.

Cell strain energy costs of active control of contractility

The paper develops a theoretical model showing that increasing cell contractility on stiffer substrates can be energetically efficient through feedback mechanisms and adhesion changes.

A spatially resolved mechanistic growth law for cancer drug development.

The paper presents a mechanistic tumor growth model for drug development that predicts spatial cell subpopulation distributions and integrates with existing pre-clinical workflows.

Mapping the mechanical microenvironment in the ovary

The paper maps the mechanical microenvironment in mouse ovaries using AFM, finding stiffness varies spatially with large follicles being mechanically dominant.

Sticking around: Optimal cell adhesion patterning for energy minimization and substrate mechanosensing

This paper shows that cell stiffness sensing depends on adhesion patterning, not just substrate stiffness, and demonstrates energy-based adhesion dynamics on different substrates.