Author

J. A. Burdick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 7 Biophysics· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 9 Research Focus:cell type annotation· 7 Organism:human· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:development & morphogenesis· 3 Assay:organoid / primary culture· 3 Research Focus:trajectory inference· 3 Research Focus:differential expression· 2

Frequent Co-Authors

M. D. Davidson· 4 shared A. C. Daly· 2 shared A. Dhand· 2 shared C. Loebel· 2 shared K. L. Xu· 2 shared R. L. Mauck· 2 shared S. L. Vega· 2 shared S.-J. Heo· 2 shared

Activity by Year

2020-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersBioengineering

M. D. Davidson

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Emergence of active contractile patterns alters monolayer force generation and transmission in response to focal adhesion distribution

J. R. Davis, J. Solowiej-Wedderburn, S. L. Vega, J. A. Burdick, C. Dunlop, N. Tapon

This study shows that focal adhesion distribution affects force balance in epithelial monolayers, revealing non-uniform contractile patterns that alter force transmission.

bioRxiv · Apr 10, 2024 · PreprintBiophysics

Microinterfaces in bicontinuous hydrogels guide rapid 3D cell migration

K. L. Xu, N. d. Caprio, H. Fallahi, M. Dehgany, M. D. Davidson, B. C. Cheung, L. Laforest, M. Wu, V. Shenoy, L. Han, R. L. Mauck, J. A. Burdick

This study develops a bicontinuous hydrogel system that enables rapid 3D cell migration by leveraging microinterfaces, showing mesenchymal behavior across multiple contexts.

bioRxiv · Sep 28, 2023 · PreprintBioengineering

Injectable MSC Spheroid and Microgel Granular Composites for Engineering Cartilage Tissue

N. Di Caprio, M. D. Davidson, A. C. Daly, J. A. Burdick

This paper develops injectable granular composites of MSC spheroids and microgels for cartilage tissue engineering, showing they can produce cartilage with native properties.

bioRxiv · Dec 28, 2022 · PreprintBioengineering

Injury and a program of fetal wound healing in the fetal and neonatal extrahepatic bile duct

I. E. M. de Jong, M. L. Hunt, D. Chen, Y. Du, J. Llewellyn, K. Gupta, D. A. Erxleben, F. Rivas, A. R. Hall, E. E. Furth, A. Naji, C. Liu, A. Dhand, J. A. Burdick, M. G. Davey, , R. G. Wells

This study investigates the fetal response to injury in extrahepatic bile ducts (EHBDs) and identifies a fetal wound healing program characterized by high molecular weight HA, which may lead to obstruction in biliary atresia.

bioRxiv · Dec 15, 2022 · PreprintPhysiology

Engineered hydrogel reveals contribution of matrix mechanics to esophageal adenocarcinoma 3D organoids and identify matrix-activated therapeutic targets

R. Cruz-Acuna, S. W. Kariuki, K. Sugiura, C. Loebel, T. Karakasheva, J. T. Gabre, J. A. Burdick, A. K. Rustgi

The paper develops a hydrogel platform to study matrix mechanics in EAC organoids and identifies therapeutic targets for ECM stiffness.

bioRxiv · Nov 13, 2022 · PreprintBioengineering

Mechanotransductive feedback control of endothelial cell motility and vascular morphogenesis

D. E. Mason, P. Camacho, M. Goeckel, B. R. Tobin, S. L. Vega, P.-H. Wu, D. Johnson, S.-J. Heo, D. Wirtz, J. A. Burdick, L. Wood, B. Y. Chow, A. N. Stratman, J. D. Boerckel

This study identifies a mechanotransductive feedback loop involving YAP and TAZ that regulates endothelial cell motility and vascular morphogenesis in vitro and in vivo.

bioRxiv · Jun 15, 2022 · PreprintCell Biology

Dopaminergic axon tracts within a hyaluronic acid hydrogel encasement for implantation to restore the nigrostriatal pathway

W. J. Gordian-Velez, K. D. Browne, J. H. Galarraga, J. E. Duda, R. A. Espana, H. I. Chen, J. A. Burdick, D. K. Cullen

This paper develops a hyaluronic acid hydrogel-based tissue-engineered nigrostriatal pathway to restore dopamine function in Parkinson's disease by improving axon growth and reducing inflammation.

bioRxiv · Jul 3, 2021Bioengineering

Chemo-Mechanical Cues Modulate Nano-Scale Chromatin Organization in Healthy and Diseased Connective Tissue Cells

S.-J. Heo, S. Thakur, X. Chen, C. Loebel, B. Xia, R. McBeath, J. A. Burdick, V. B. Shenoy, R. L. Mauck, M. Lakadamyali

This study shows that chemo-mechanical cues influence chromatin organization in connective tissue cells, with disease disrupting this relationship.

bioRxiv · Apr 27, 2021 · PreprintBioengineering

Programmable and Contractile Materials Through Cell Encapsulation in Fibrous Hydrogel Assemblies

M. D. Davidson, M. E. Prendergast, E. Ban, K. L. Xu, G. Mickel, P. Mensah, A. Dhand, P. A. Janmey, V. B. Shenoy, J. A. Burdick

This paper develops fibrous hydrogel assemblies that contract when encapsulated with mesenchymal stromal cells, enabling programmed shape changes for biofabrication and tissue engineering.

bioRxiv · Apr 19, 2021Bioengineering

3D bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels

A. C. Daly, M. D. Davidson, J. A. Burdick

This paper develops a bioprinting method to create high-cell-density, heterogeneous tissue models by fusing spheroids in self-healing hydrogels, demonstrating its application in cardiac tissue regeneration studies.

bioRxiv · May 21, 2020Bioengineering