C. E. Miles

ADP release can explain spatially-dependent kinesin binding times

This paper identifies ADP release as a rate-limiting factor in kinesin-microtubule binding using experimental data and computational models.

Mechanical torque promotes bipolarity of the mitotic spindle through multi-centrosomal clustering

The paper investigates how mechanical torque influences mitotic spindle bipolarity by modeling centrosome interactions and showing torque promotes stable bipolar configurations.

kSHREC ‘Delta’ reflects the shape of kinetochore rather than intrakinetochore tension

The paper investigates whether Delta reflects intrakinetochore tension or kinetochore shape by comparing Delta values in Indian muntjac and human cells under different conditions.

A unified role for membrane-cortex detachment during cell protrusion initiation

The paper shows that membrane-cortex detachment is essential for initiating both pressure-based and actin-based protrusions, challenging the Brownian ratchet model and unifying protrusion regulation.