PAF1 facilitates RNA polymerase II ubiquitination by the Elongin A complex through phosphorylation by CDK12
G. Sanchez, J. Barbier, C. Elie, R. Kiernan, S. Rouquier
The paper shows PAF1 interacts with Elongin A to ubiquitinate RNA polymerase II, dependent on CDK12-mediated Ser2 phosphorylation of the CTD.
bioRxiv · Sep 17, 2020 · PreprintCell Biology