A single binge ethanol exposure is apoptotic within hours across neurodevelopment and partially regulated by the Myt1l gene.
Nicole A. Fuhler, Cory Palmer, Gianna Tunzi, Lilly Tian, Maya Fotedar, Rebecca Chase, Ramachandran Prakasam, Susan E. Maloney, C. Eric Neblock, Jiayang Chen, Kristen L. Kroll, Joseph D. Dougherty, Kevin K. Noguchi
The paper shows a single binge ethanol exposure rapidly increases apoptosis in early adolescent and adult mice, with Myt1l haploinsufficiency modulating this effect across developmental stages.
bioRxiv · Jun 27, 2025 · PreprintNeuroscience