Author

C. F. Spiropoulou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

D. Wentworth· 1 shared G. Ho· 1 shared J. Montgomery· 1 shared J. R. Beadle· 1 shared K. Y. Hostetler· 1 shared L. J. Rennick· 1 shared M. Flint· 1 shared M. K. Lo· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

D. Wentworth

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2 papers

Recent·Most cited

MicrobiologymSpherePeer-reviewedOct 27, 2021

Sustained replication of synthetic canine distemper virus defective genomes in vitro and in vivo

N. Tilston-Lunel, S. R. Welch, S. Nambulli…·W. P. Duprex

This paper generates and characterizes defective interfering genomes of canine distemper virus, showing their sustained replication in vivo and potential as therapeutic agents.

DOI 10.1128/msphere.00537-21

experimental assay

Pharmacology & ToxicologybioRxivAug 6, 2021

Broad-spectrum in vitro antiviral activity of ODBG-P-RVn: an orally-available, lipid-modified monophosphate prodrug of remdesivir parent nucleoside (GS-441524)

M. K. Lo, P. Shrivastava-Ranjan, P. Chatterjee…·C. F. Spiropoulou

This study evaluates the antiviral activity of ODBG-P-RVn, an orally available prodrug of remdesivir, against SARS-CoV-2 and other viruses in human airway cells, showing improved efficacy compared to GS-441524.

DOI 10.1128/spectrum.01537-21

humanexperimental assay