Impact of efavirenz, ritonavir-boosted lopinavir and nevirapine based antiretroviral regimens on the pharmacokinetics of lumefantrine and safety of artemether-lumefantrine in falciparum-negative HIV-infected Malawian adults stabilized on antiretroviral therapy
C. G. Banda, F. K. Dzinjalamala, M. Mukaka, J. Mallewa, V. Maiden, D. J. Terlouw, D. G. Lalloo, S. Khoo, V. Mwapasa
This study evaluates how different antiretroviral therapies affect lumefantrine pharmacokinetics and the safety of artemether-lumefantrine in HIV-infected adults, finding significant variations in lumefantrine exposure and safety profiles.
bioRxiv · Jun 3, 2018Pharmacology & Toxicology