Author

C. Gurcan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

A. Yilmazer· 3 shared A. OZKUL· 2 shared C. V. BITIRIM· 2 shared E. DEMIR· 2 shared E. KOCAKAYA· 2 shared G. Y. SUMMAK· 2 shared H. NAZIR· 2 shared J. SOMERS· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersPharmacology & Toxicology

A. Yilmazer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Predicting the Reprogrammability of Human Cells Based on Transcriptome Data and SGD Classifier with Elastic-Net Regularization

G. Saygili, M. Turktas, C. Gurcan, L. G. Delogu, A. Yilmazer

This study predicts cell reprogramming outcomes using transcriptome data and an SGD classifier with Elastic-Net regularization, achieving 98% accuracy and 0.98 AUC.

bioRxiv · Jul 18, 2022 · PreprintBioengineering

Hemin shows antiviral activity in vitro, possibly through suppression of viral entry mediators.

M. A. UNAL, C. V. BITIRIM, J. SOMERS, G. Y. SUMMAK, O. BUL BESBINAR, E. KOCAKAYA, C. GURCAN, H. NAZIR, Z. B. Aksoy Ozer, S. A. OZKAN, S. BEREKETOGLU, A. OZKUL, E. DEMIR, K. C. AKCALI, A. YILMAZER

This study shows Hemin reduces SARS-CoV-2 infectivity in Vero E6 cells by decreasing TMPRSS2 and ACE2 expression.

bioRxiv · May 24, 2022 · PreprintPharmacology & Toxicology

Ribavirin shows antiviral activity against SARS-CoV-2 and downregulates the activity of TMPRSS2 and the expression of ACE2 in vitro

M. A. Unal, C. V. Bitirim, G. Y. Summak, S. Bereketoglu, I. Cevher Zeytin, O. Besbinar, C. Gurcan, D. Aydos, E. Goksoy, E. Kocakaya, Z. Eran, M. Murat, N. Demir, J. Somers, E. Demir, , K. C. Akcali

bioRxiv · Dec 4, 2020Pharmacology & Toxicology