Author

K. C. Akcali

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. YILMAZER· 3 shared G. Y. SUMMAK· 3 shared H. NAZIR· 3 shared M. A. UNAL· 3 shared S. A. OZKAN· 3 shared A. OZKUL· 2 shared C. GURCAN· 2 shared C. V. BITIRIM· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersPharmacology & Toxicology

A. YILMAZER

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Hemin shows antiviral activity in vitro, possibly through suppression of viral entry mediators.

M. A. UNAL, C. V. BITIRIM, J. SOMERS, G. Y. SUMMAK, O. BUL BESBINAR, E. KOCAKAYA, C. GURCAN, H. NAZIR, Z. B. Aksoy Ozer, S. A. OZKAN, S. BEREKETOGLU, A. OZKUL, E. DEMIR, K. C. AKCALI, A. YILMAZER

This study shows Hemin reduces SARS-CoV-2 infectivity in Vero E6 cells by decreasing TMPRSS2 and ACE2 expression.

bioRxiv · May 24, 2022 · PreprintPharmacology & Toxicology

Favipiravir, umifenovir and camostat mesylate: a comparative study against SARS-CoV-2

M. A. Unal, O. Besbinar, H. Nazir, G. Y. Summak, F. Bayrakdar, L. G. Delogu, T. Taskin, S. A. Ozkan, K. C. Akcali, A. Yilmazer

This study compares the antiviral effects of favipiravir, umifenovir, and camostat mesylate against SARS-CoV-2 using in silico and in vitro methods, finding that combination treatments are more effective than single drugs.

bioRxiv · Jan 11, 2022 · PreprintPharmacology & Toxicology

Ribavirin shows antiviral activity against SARS-CoV-2 and downregulates the activity of TMPRSS2 and the expression of ACE2 in vitro

M. A. Unal, C. V. Bitirim, G. Y. Summak, S. Bereketoglu, I. Cevher Zeytin, O. Besbinar, C. Gurcan, D. Aydos, E. Goksoy, E. Kocakaya, Z. Eran, M. Murat, N. Demir, J. Somers, E. Demir, , K. C. Akcali

bioRxiv · Dec 4, 2020Pharmacology & Toxicology