Author

C. H. Lo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

D. Basanta· 2 shared E. Baratchart· 2 shared C. C. Lynch· 1 shared C. Lynch· 1 shared E. N. Saipuljumri· 1 shared G. W. Z. Loi· 1 shared J. Indajang· 1 shared J. Zeng· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

D. Basanta

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Acidic nanoparticles restore lysosomal acidification and rescue metabolic dysfunction in pancreatic β-cells under lipotoxic condition

C. H. Lo, L. M. O'Connor, G. W. Z. Loi, E. N. Saipuljumri, J. Indajang, K. M. Lopes, O. S. Shirihai, M. W. Grinstaff, J. Zeng

This study develops TFSA nanoparticles that restore lysosomal acidification and improve metabolic function in pancreatic β-cells under lipotoxic conditions.

bioRxiv · Jul 11, 2023Bioengineering

Integrated computational and in vivo models reveal Key Insights into Macrophage Be-havior during bone healing

E. Baratchart, C. H. Lo, C. Lynch, D. Basanta

This study uses a mathematical framework to analyze bone healing dynamics, revealing roles of pro- and anti-inflammatory macrophages in osteoclast and osteoblast behavior.

bioRxiv · Dec 9, 2021Immunology

Computational modeling reveals a key role for polarized myeloid cells in controlling osteoclast activity during bone injury repair

C. H. Lo, E. Baratchart, D. Basanta, C. C. Lynch

The paper uses an ODE model to show that pro- and anti-inflammatory myeloid cells are essential for bone repair by regulating osteoclast activity beyond just osteoblast/osteoclast numbers.

bioRxiv · Oct 13, 2020Physiology