Author

C. H. Wallace

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:imaging· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

B. Jones· 1 shared G. Oliveros· 1 shared L. Xie· 1 shared M. Figueiredo-Pereira· 1 shared O. Chaudry· 1 shared P. A. Serrano· 1 shared P. Rockwell· 1 shared Q. Liu· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPhysiology

B. Jones

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2 papers

Recent·Most cited

Diaphragm muscle fibrosis involves changes in collagen organization with mechanical implications in Duchenne Muscular Dystrophy

R. Sahani, C. H. Wallace, B. Jones, S. S. Blemker

This study examines collagen organization changes in diaphragm muscle of DMD mice, showing increased fiber straightness and stiffness with disease progression.

bioRxiv · Apr 7, 2021Physiology

Multi-scale predictive modeling discovers Ibudilast as a polypharmacological agent to improve hippocampal dependent spatial learning and memory and mitigate plaque and tangle pathology in a transgenic rat model of Alzheimer's disease

G. Oliveros, C. H. Wallace, O. Chaudry, Q. Liu, Y. Qiu, L. Xie, P. Rockwell, M. Figueiredo-Pereira, P. A. Serrano

The paper uses multi-scale predictive modeling to identify ibudilast as a potential therapeutic for Alzheimer's disease by improving cognition and reducing pathology in a transgenic rat model.

bioRxiv · Apr 6, 2021 · PreprintPharmacology & Toxicology