Author

C. H. Wu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

C. Sahinalp· 2 shared S. Malikic· 2 shared A. Castro· 1 shared A. Fon· 1 shared A. Sassano· 1 shared C. Gruen· 1 shared C. Marcelus· 1 shared C. Smith· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

C. Sahinalp

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Author profile →

2 papers

Recent·Most cited

Determining Optimal Placement of Copy Number Aberration Impacted Single Nucleotide Variants in a Tumor Progression History

C. H. Wu, S. Joshi, W. Robinson, P. F. Robbins, R. Schwartz, C. Sahinalp, S. Malikic

This paper introduces DETOPT, a method for accurately placing SNVs affected by CNAs in tumor progression trees, showing improved accuracy on simulated data and biologically plausible results on breast cancer metastases.

bioRxiv · Mar 10, 2024 · PreprintCancer Biology

Melanoma clonal subline analysis uncovers heterogeneity-driven immunotherapy resistance mechanisms

C. Gruen, H. H. Yang, A. Sassano, E. Wu, V. Gopalan, K. L. Marie, A. Castro, F. R. Mehrabadi, C. H. Wu, I. Church, G. A. Needle, C. Smith, S. Chin, J. Ebersole, C. Marcelus, , E. Perez-Guijarro

The paper analyzes melanoma clonal sublines to uncover how intratumoral heterogeneity drives resistance to immunotherapy.

bioRxiv · Apr 3, 2023 · PreprintCancer Biology