Author

C. Hirtz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

J. Vialaret· 2 shared A. AMALRIC· 1 shared A. ATTINA· 1 shared A. BASTIDE· 1 shared A. Caballero Megido· 1 shared A. CHOQUET· 1 shared A. Cryar· 1 shared A. DAVID· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersPathology

J. Vialaret

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Inherited mitochondrial dysfunction triggered by OPA1 mutation impacts the sensory innervation fibre identity, functionality and regenerative potential in the cornea

L. Meneux, N. Feret, S. Pernot, M. Girard, S. Sarkis, A. Caballero Megido, M. Quiles, L. Fichter, J. Vialaret, C. Hirtz, C. Delettre, F. Michon

This study shows that OPA1 mutation causes corneal innervation issues, including reduced sensitivity and impaired regeneration, despite normal epithelial function.

bioRxiv · Apr 18, 2024 · PreprintPathology

A candidate reference method for the quantification of α-synuclein in cerebrospinal fluid using an SI traceable primary calibrator and multiple reaction monitoring

L. Zhang, E. Iles-Toth, A. Cryar, G. Drinkwater, L. Di Vagno, M.-L. Pons, J. Mateyka, B. McCullough, E. Achtar, C. Clarkson, L. Goeschel, P. Koertvelyessy, C. Mussell, C. Hopley, A. Floeel, , M. Quaglia

This paper develops a reference method for quantifying α-synuclein in CSF using SI-traceable calibration and MRM, showing linearity across three orders of magnitude.

bioRxiv · Mar 20, 2024Biochemistry

FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell

S. RELIER, J. RIPOLL, H. GUILLORIT, A. AMALRIC, F. BOISSIERE, J. VIALARET, A. ATTINA, F. DEBART, A. CHOQUET, F. MACARI, E. SAMALIN, J.-J. VASSEUR, J. PANNEQUIN, E. CRAPEZ, C. HIRTZ, , A. DAVID

This study shows FTO-mediated m6Am demethylation reduces CSC properties in colorectal cancer by affecting translation efficiency, not transcriptome remodeling.

Nature Communications · Mar 19, 2021Peer-reviewedCancer Biology