An insulin-stimulated proteolytic mechanism links energy expenditure with glucose uptake
E. N. Habtemichael, D. T. Li, J. P. Camporez, X. O. Westergaard, C. I. Sales, X. Liu, F. Lopez-Giraldez, S. G. DeVries, H. Li, D. M. Ruiz, K. Y. Wang, B. S. Sayal, S. Hirabara, D. F. Vatner, W. Philbrick, , J. S. Bogan
This study identifies an insulin-stimulated proteolytic mechanism linking energy expenditure with glucose uptake through TUG cleavage and its nuclear effects.
bioRxiv · Nov 12, 2019Physiology