Mutational analysis of the structure and function of the chaperone domain of UNC-45B
I. Gaziova, T. Moncrief, C. J. Christian, M. A. White, M. A. Villarreal, S. Powell, H. Qadota, G. Benian, A. F. Oberhauser
This paper investigates the chaperone function of UNC-45B's UCS domain by engineering mutations and analyzing their effects on structure, stability, and sarcomere organization in C. elegans and human cataract.
bioRxiv · Jan 3, 2020Biophysics