Author

S. Powell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1 Evolutionary Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 3 Organism:human· 2 Research Focus:protein structure prediction· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Organism:chicken / avian· 1

Frequent Co-Authors

F. Margadant· 2 shared I. V. Novikova· 2 shared J. E. Evans· 2 shared M. Sheetz· 2 shared M. Zhou· 2 shared A. F. Oberhauser· 1 shared A. Hariharan· 1 shared A. Maisha· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersPhysiology

F. Margadant

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Rejuvenation of Senescent Cells by Low Frequency Ultrasound without Senolysis

S. K. Kureel, R. Maroto, S. Powell, F. Margadant, B. Blair, A. Maisha, B. Rasmussen, M. Sheetz

Low-frequency ultrasound rejuvenates senescent cells by reversing 15 characteristics, including autophagy activation and reduced SASP secretion, improving healthspan in mice.

bioRxiv · Dec 8, 2022Physiology

Cryo-EM structure of the diapause chaperone artemin

A. Parvate, S. Powell, J. Brookreson, T. Moser, I. V. Novikova, M. Zhou, J. E. Evans

The paper reports the cryo-EM structure of artemin, revealing its intramolecular disulfide bond and C-terminal helix's role in dimer stabilization.

bioRxiv · Apr 6, 2022Biochemistry

Structure Of Eukaryotic Type III Glutamine Synthetase Lacking Ring-Ring Quaternary Contacts

I. V. Novikova, S. Powell, C. Smallwood, S. O. Purvine, M. Zhou, J. E. Evans

The paper reports the cryo-EM structure of eukaryotic GSIII from Ostreococcus tauri and shows it forms a single hexameric ring, differing from other GS classes.

bioRxiv · Apr 5, 2022 · PreprintBiochemistry

The secrets to domestic bliss - Partner fidelity and environmental filtering preserve stage-specific turtle ant gut symbioses for over 40 million years

Y. Hu, C. L. D'Amelio, B. Bechade, C. S. Cabuslay, J. G. Sanders, S. Price, E. Fanwick, S. Powell, C. Moreau, J. A. Russell

bioRxiv · Sep 13, 2021 · PreprintEvolutionary Biology

MCM complexes are barriers that restrict cohesin-mediated loop extrusion

B. J. H. Dequeker, H. B. Brandao, M. J. Scherr, J. Gassler, S. Powell, I. Gaspar, I. M. Flyamer, W. Tang, R. Stocsits, I. F. Davidson, J.-M. Peters, K. E. Duderstadt, L. A. Mirny, K. Tachibana

The paper shows MCM complexes block cohesin-mediated loop extrusion, reducing CTCF-anchored loops and TAD boundary insulation in G1 phase.

bioRxiv · Oct 15, 2020Cell Biology

Ultrasound-mediated mechanical forces selectively kill tumor cells

A. Tijore, F. Margadant, M. Yao, A. Hariharan, C. A. Z. Chew, S. Powell, G. K. Bonney, M. Sheetz

This paper shows low-frequency ultrasound selectively kills tumor cells via a calpain-dependent mitochondrial pathway involving Piezo1 channels, with minimal damage to normal cells in animal models and patient-derived organoids.

bioRxiv · Oct 9, 2020 · PreprintCancer Biology

Mutational analysis of the structure and function of the chaperone domain of UNC-45B

I. Gaziova, T. Moncrief, C. J. Christian, M. A. White, M. A. Villarreal, S. Powell, H. Qadota, G. Benian, A. F. Oberhauser

This paper investigates the chaperone function of UNC-45B's UCS domain by engineering mutations and analyzing their effects on structure, stability, and sarcomere organization in C. elegans and human cataract.

bioRxiv · Jan 3, 2020Biophysics