Interferon-Induced Transmembrane Proteins Inhibit Infection by the Kaposis Sarcoma-Associated Herpesvirus and the Related Rhesus Monkey Rhadinovirus in a Cell Type-Specific Manner.
B. F. Hörnich, A. K. Grosskopf, C. J. DCosta, S. Schlagowski, A. S. Hahn
This study identifies IFITM1 as a cell type-dependent inhibitor of KSHV and RRV infection, acting at the membrane fusion stage, and shows that HUVEC resist IFITM restriction despite high expression.
bioRxiv · Jul 16, 2021Microbiology