A. S. Hahn

Kaposi's sarcoma-associated herpesvirus (KSHV) gB dictates a low-pH endocytotic entry pathway as revealed by a dual-fluorescent virus system and a rhesus monkey rhadinovirus expressing KSHV gB

This paper develops fluorescent KSHV strains and a hybrid RRV expressing KSHV gB to show low pH is required for KSHV membrane fusion during endocytosis.

Tim-1 and Tim-4 mediate entry of the human Kaposi's sarcoma-associated herpesvirus and the related rhesus monkey rhadinovirus

This paper identifies Tim-1 and Tim-4 as mediators of KSHV and RRV entry, showing their role in viral infection and highlighting their unique function compared to other herpesviruses.

Kaposi's sarcoma-associated herpesvirus glycoprotein K8.1 is critical for infection in a cell-specific manner and functions at the attachment step on keratinocytes

This study shows K8.1 is critical for KSHV infection in epithelial cells but not in B cells, functioning at the attachment step.

Interferon-Induced Transmembrane Proteins Inhibit Infection by the Kaposis Sarcoma-Associated Herpesvirus and the Related Rhesus Monkey Rhadinovirus in a Cell Type-Specific Manner.

This study identifies IFITM1 as a cell type-dependent inhibitor of KSHV and RRV infection, acting at the membrane fusion stage, and shows that HUVEC resist IFITM restriction despite high expression.

SARS-CoV-2 and SARS-CoV spike-mediated cell-cell fusion differ in the requirements for receptor expression and proteolytic activation

This study compares the requirements for receptor expression and proteolytic activation in SARS-CoV-2 and SARS-CoV spike-mediated cell-cell fusion, revealing differences in their dependence on ACE2, TMPRSS2, and metalloproteases.

Plxdc family members are novel receptors for the rhesus monkey rhadinovirus (RRV)

This study identifies Plxdc1/2 as novel receptors for RRV, distinguishing it from KSHV and highlighting a conserved N-terminal motif in RRV gH/gL.

EphA7 functions as a receptor for cell-to-cell transmission of Kaposi’s sarcoma-associated herpesvirus into BJAB B cells and for cell-free virus infection by the related rhesus monkey rhadinovirus

This paper identifies EphA7 as the critical receptor for KSHV cell-to-cell transmission into BJAB B cells and for RRV cell-free infection, showing functional conservation between these viruses.