Author

C. J. Hsiao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Organism:human· 1 Assay:multiome· 1 Organism:non-human primate· 1 Assay:protein sequence· 1

Frequent Co-Authors

A. Carfi· 4 shared D. K. Edwards· 2 shared K. Bahl· 2 shared A. Bukreyev· 1 shared A. Cadete· 1 shared A. Choi· 1 shared A. F. Richards· 1 shared A. Golding· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersImmunology

A. Carfi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Intranasal mRNA-LNP vaccination protects hamsters from SARS-CoV-2 infection

G. Baldeon Vaca, M. Meyer, A. Cadete, C. J. Hsiao, A. Golding, A. Jeon, E. Jacquinet, E. Azcue, C. M. Guan, X. Sanchez-Felix, C. A. Pietzsch, C. E. Mire, M. A. Hyde, M. E. Comeaux, J. M. Williams, , K. Bahl

This study shows intranasal mRNA-LNP vaccination protects hamsters from SARS-CoV-2 by inducing antibodies and reducing viral load and lung damage.

bioRxiv · Jan 11, 2023 · PreprintImmunology

mRNA delivery of dimeric human IgA protects mucosal tissues from bacterial infection

C. E. Deal, A. F. Richards, T. Yeung, M. J. Maron, Z. Wang, Y.-T. Lai, B. R. Fritz, S. Himansu, E. Narayanan, D. Liu, R. Koleva, S. Licht, C. J. Hsiao, I. L. Rajlic, H. Koch, , O. J. Plante

The paper demonstrates that mRNA-delivered human IgA can protect mucosal tissues from bacterial infection by trafficking to mucosal sites and limiting bacterial invasion.

bioRxiv · Jan 3, 2023 · PreprintImmunology

An optimized messenger RNA vaccine candidate protects non-human primates from Zika virus infection

B. A. Bollman, N. Nunna, K. Bahl, C. J. Hsiao, H. Bennett, S. Butler, B. Foreman, K. E. Burgomaster, M. Aleshnick, W.-P. Kong, B. E. Fisher, T. J. Ruckward, K. M. Morabito, B. S. Graham, K. A. Dowd, , A. Carfi

This study compares two ZIKV mRNA vaccines, showing that mRNA-1893 provides complete protection at a lower dose than mRNA-1325 in non-human primates.

bioRxiv · Oct 11, 2022 · PreprintImmunology

Development of SARS-CoV-2 mRNA vaccines encoding spike N-terminal and receptor binding domains

G. Stewart-Jones, S. M. Elbashir, K. Wu, D. Lee, I. Renzi, B. Ying, M. Koch, C. E. Sein, A. Choi, B. Whitener, D. Garcia-Dominguez, C. Henry, A. Woods, L. Ma, D. Montes Berrueta, , A. Carfi

The paper develops and evaluates an mRNA vaccine, mRNA-1283, encoding SARS-CoV-2 spike N-terminal and receptor-binding domains, showing improved immunogenicity and protection against multiple variants in mice.

bioRxiv · Oct 7, 2022 · PreprintImmunology