Meta-analyses of mouse and human prostate single-cell transcriptomes reveal widespread epithelial plasticity in tissue regression, regeneration, and cancer
L. Aparicio, L. Crowley, J. R. Christin, C. J. Laplaca, H. Hibshoosh, R. Rabadan, M. M. Shen
This study uses scRNA-seq data from mouse and human prostate tissues to show epithelial plasticity in regression, regeneration, and cancer, with findings on cell type origins and AR signaling heterogeneity.
bioRxiv · Jan 30, 2024Cancer Biology