Author

C. J. Sumby

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Biochemistry· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. D. Abell· 1 shared A. P. Thompson· 1 shared B. I. Gaiser· 1 shared J. B. Bruning· 1 shared K. J. Lee· 1 shared K. L. Wegener· 1 shared M. T. Huxley· 1 shared S. W. Polyak· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

A. D. Abell

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1 paper

Recent·Most cited

Fortuitous in vitro compound degradation produces a tractable hit against Mycobacterium tuberculosis dethiobiotin synthetase: a cautionary tale of what goes in, does not always come out

W. Salaemae, A. P. Thompson, B. I. Gaiser, K. J. Lee, M. T. Huxley, C. J. Sumby, S. W. Polyak, A. D. Abell, J. B. Bruning, K. L. Wegener

The paper describes how a fragment compound was inadvertently modified in crystal conditions, leading to a potent inhibitor of Mycobacterium tuberculosis dethiobiotin synthetase.

bioRxiv · Mar 26, 2023 · PreprintBiochemistry