Author

A. D. Abell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. C. Zannettino· 1 shared A. Emery· 1 shared A. J. Shepherd· 1 shared A. P. Thompson· 1 shared B. I. Gaiser· 1 shared C. Aguilar· 1 shared C. J. Sumby· 1 shared D. J. L. Turner· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCell Biology

A. C. Zannettino

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

N-cadherin mechanosensing in ovarian follicles controls oocyte maturation and ovulation

A. Emery, O. W. Blaschuk, D. T. Dinh, T. McPhee, R. Becker, A. D. Abell, K. M. Mrozik, A. C. Zannettino, R. Robker, D. L. Russell

This study shows N-cadherin mechanosensing regulates ovarian follicle structure, oocyte maturation, and ovulation by modulating Hippo/YAP and β-catenin pathways.

bioRxiv · Oct 6, 2023Cell Biology

Fortuitous in vitro compound degradation produces a tractable hit against Mycobacterium tuberculosis dethiobiotin synthetase: a cautionary tale of what goes in, does not always come out

W. Salaemae, A. P. Thompson, B. I. Gaiser, K. J. Lee, M. T. Huxley, C. J. Sumby, S. W. Polyak, A. D. Abell, J. B. Bruning, K. L. Wegener

The paper describes how a fragment compound was inadvertently modified in crystal conditions, leading to a potent inhibitor of Mycobacterium tuberculosis dethiobiotin synthetase.

bioRxiv · Mar 26, 2023 · PreprintBiochemistry

Drug targeting to sites of oxidative stress using the Baeyer-Villiger reaction

T. D. Avery, J. Li, D. J. L. Turner, F. R. Cherry, M. S. Ur Rasheed, C. Aguilar, A. J. Shepherd, J. Yu, P. M. Grace, A. D. Abell

The paper develops a 1,2-dicarbonyl compound that selectively activates Nrf2 at sites of oxidative stress, reversing pain in mice and offering a targeted approach for treating oxidative stress-related disorders.

bioRxiv · Sep 3, 2021 · PreprintPharmacology & Toxicology