Structural basis of CMKLR1 signaling induced by chemerin9
C. Zhang, X. Zhang, T. Weiss, M. H. Cheng, S. Chen, C. K. Ambrosius, A. S. Czerniak, K. Li, M. Feng, I. Bahar, A. G. Beck-Sickinger
The paper determines the cryo-EM structure of the CMKLR1-Gi complex with chemerin9, revealing molecular mechanisms of signaling and potential for small molecule agonist development.
bioRxiv · Jun 9, 2023 · PreprintBiophysics