C. K. Voong

RNA- and DNA-binding proteins generally exhibit direct transfer of polynucleotides: Implications for target site search

The paper demonstrates that RNA- and DNA-binding proteins can directly transfer polynucleotides, enabling one-dimensional target site search and suggesting regulated complex lifetimes in vivo.

Single molecule studies characterize the kinetic mechanism of tetrameric p53 binding to different native response elements

This study uses single molecule fluorescence to analyze p53 tetramer binding dynamics to five native response elements, revealing two kinetically distinct populations and sequence-dependent dissociation rates.