Autoregulation of a trimeric transporter involves the cytoplasmic domains of both adjacent subunits
V. Leone, R. T. Bradshaw, C. Koshy, P. S. Lee, C. Fenollar-Ferrer, V. Heinz, C. Ziegler, L. R. Forrest
This study uses molecular simulations to analyze the autoregulatory domains of BetP, showing how C-terminal tails interact with neighboring subunits and how N-terminal tails may also contribute to regulation.
bioRxiv · Jun 5, 2022Biochemistry