Author

R. T. Bradshaw

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

L. R. Forrest· 2 shared V. Leone· 2 shared C. Fenollar-Ferrer· 1 shared C. Koshy· 1 shared C. Ziegler· 1 shared F. Marinelli· 1 shared G. Rudnick· 1 shared J. D. Faraldo-Gomez· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

L. R. Forrest

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Autoregulation of a trimeric transporter involves the cytoplasmic domains of both adjacent subunits

V. Leone, R. T. Bradshaw, C. Koshy, P. S. Lee, C. Fenollar-Ferrer, V. Heinz, C. Ziegler, L. R. Forrest

This study uses molecular simulations to analyze the autoregulatory domains of BetP, showing how C-terminal tails interact with neighboring subunits and how N-terminal tails may also contribute to regulation.

bioRxiv · Jun 5, 2022Biochemistry

Chloride-dependent conformational changes in the GlyT1 glycine transporter

Y.-W. Zhang, S. Uchendu, V. Leone, R. T. Bradshaw, N. Sangwa, L. Forrest, G. Rudnick

This study investigates how chloride ions influence conformational changes in the GlyT1 glycine transporter by analyzing ligand binding and structural shifts in response to ions and substrates.

bioRxiv · Aug 20, 2020Biochemistry

Structural Interpretation of Hydrogen-Deuterium Exchange with Maximum-Entropy Simulation Reweighting

R. T. Bradshaw, F. Marinelli, J. D. Faraldo-Gomez, L. R. Forrest

This paper introduces HDXer, a method to generate structural ensembles from HDX-MS data using maximum-entropy reweighting, demonstrating its ability to recover accurate structural information from simulated data.

bioRxiv · Sep 14, 2019Biophysics